Enter Michael. Michael did not want just cosmetic changes in the book. He proposed a radical re-envisioning of its mission: to educate students to appreciate and participate in developmental biology. One other thing that has changed in the past decade is the realization of how much our understanding of biology depends on our knowledge of development. The original theories of evolution concerned themselves with how new variants arose from the altered development of ancestors.
Also during this Victorian age, a variant of developmental biology grew to become the field of immunology. Elie Metchnikoff who showed the pole cells of flies to be germ cell precursors and who studied gastrulation throughout the animal kingdom proposed a new cell theory of immunology in his attempt to find universal characters of the embryonic and larval mesoderm.
Similarly, but with more anguish, genetics directly descended from a generation of embryologists who dealt with whether the nucleus or cytoplasm contained the determinants of embryonic development. Before his association with Drosophila, Thomas Hunt Morgan was a well-known embryologist who worked on sea urchin embryos, wrote a textbook on frog development, and was an authority on regeneration. Many of the first geneticists were originally embryologists, and it was only in the s that Morgan formally separated the two fields.
And regeneration is still intimately linked with development, for regeneration often is a recapitulation of embryonic processes. Ross Granville Harrison and Santiago Ramon y Cajal founded the science of neurobiology by showing how the brain and axons develop. To this day, neurology requires an understanding of the developmental origins of the central and peripheral nervous systems.
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